Table 6. Subtypes and maturation markers of dendritic cells (expressed as percentage) in different stages of COPD (stage 3 versus stages 1−2).
DC subtype | Maturation marker | COPD, stages 1−2(n = 34) | COPD, stage 3(n = 4) | P value* |
---|---|---|---|---|
BDCA1+mDCs | CD40 | 11.1 (19.5) | 0.7 (0.9) | 0.004 |
CD80 | 10.4 (16.0) | 2.1 (0.8) | 0.005 | |
CD83 | 10.1 (22.9) | 3.5 (6.03) | NS | |
CD86 | 20.5 (24.2) | 21.1 (27.3) | NS | |
BDCA3+mDCs | CD40 | 10.7 (23.8) | 0.4 (0.8) | 0.021 |
CD80 | 10.8 (23.9) | 0 (0) | N/A | |
CD83 | 14.3 (28.3) | 0.5 (0.6) | 0.008 | |
CD86 | 20.6 (21.8) | 22.2 (29.1) | NS | |
pDCs | CD40 | 3.8 (11.06) | 0.6 (0.9) | NS |
CD80 | 11.5 (15.1) | 6.2 (12.5) | NS | |
CD83 | 12.6 (14.1) | 11.2 (28.4) | 0.048 | |
CD86 | 12.02 (14.1) | 11.2 (15.3) | NS |
*Welch test. N/A: not applicable; NS: not significant.