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. 2016 Apr 8;11(4):e0150806. doi: 10.1371/journal.pone.0150806

Table 2. Baseline Characteristics of Statin-Treated Patients Stratified by Treatment Intensity.

Characteristics Total NO (%) Intensive Statin Therapy NO (%) Less Intensive Statin Therapy NO (%) P value
All patients 11,010* 5106 (46.4) 5904 (53.6) 0.002
Demographic
 Age, years
  <55 2491(22.6) 1216(23.8) 1275(21.6) 0.826
  55–64 2647(24.0) 1252(24.5) 1395(23.6)
  65–74 3177(28.8) 1400(27.4) 1777(30.1)
  ≥75 2695(24.5) 1238(24.2) 1457(24.7)
 Gender
  Female 3230(29.3) 1378(26.9) 1852(31.4) <0.001
CVD risk factors
 Prior hypertension 5921(53.8) 2848(55.8) 3073(52.0) <0.001
 Prior diabetes 2446(22.2) 1272(24.9) 1174(19.9) <0.001
 Prior dyslipidemia 7229(65.7) 3619(70.9) 3610(61.1) <0.001
 Current smoker 4118(37.4) 2041(39.9) 2077(35.2) <0.001
Medical histories
 Myocardial infarction 1239(11.3) 604(11.8) 635(10.8) 0.075
 Ischemic stroke 1136(10.3) 511(10.1) 625(10.6) 0.319
 Hemorrhagic stroke 132(1.2) 61(1.2) 71(1.2) 0.969
Clinical characteristics at admission
 Chest pain 10224(92.9) 4757(93.4) 5457(92.4) 0.058
 Cardiac arrest 137(1.2) 68(1.3) 69(1.2) 0.441
 Cardiac shock 450(4.1) 216(4.2) 234(3.9) 0.481
AMI type
 STEMI 9344(84.9) 4223(82.7) 5121(86.7) <0.001
Laboratory test
 LDL-C level, mmol/L <0.001
  < 1.81 1140(10.4) 529(10.4) 611(10.3)
  1.81–2.59 2952(26.8) 1405(27.5) 1547(26.2)
  2.60–3.37 3091(28.1) 1499(29.3) 1592(27.0)
  >3.37 2251(20.4) 1137(22.3) 1114(18.9)
 Unmeasured 1576(14.3) 536(10.5) 1040(17.6)
Economic-geographic region 0.872
 Eastern 6585(59.8) 3436(67.3) 3149(53.3)
 Central 2224(20.2) 843(16.5) 1381(23.4)
 Western 2201(20) 827(16.2) 1374(23.3)
Urban/Rural
 Rural 3708(33.7) 1165(22.8) 2543(43.1) <0.001
 Urban 7302(66.3) 3941(77.2) 3361(56.9)
Year
 2001 592(5.4) 6(0.1) 586(9.9) <0.001
 2006 2956(26.8) 729(14.3) 2227(37.7)
 2011 7462(67.8) 4371(85.6) 3091(52.4)

*Note: 11,268 patients received statin therapy; however, the dose was not documented in the medical record of 258 patients and were excluded from this table, leaving11,010 patients whose statin dose was definitively recorded.

AMI indicates acute myocardial infarction;

STEMI indicates ST-segment elevation myocardial infarction;

LDL-C indicates low density lipid cholesterol.