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. 2016 Apr 8;11(4):e0153330. doi: 10.1371/journal.pone.0153330

Fig 3. TSA or MCP30 increases the decreased acetylation of Topo IIα promoter in benzene poisoning mice.

Fig 3

After all mice were killed, bone marrow mononuclear cells were separated and histone acetylation of Topo IIα promoter was assessed with chromatin immunoprecipitation (ChIP) assay using anti-acetylated histone H3 and anti-acetylated histone H4. (A) Representatives were shown for acetylation levels of histone H3 and histone H4 in the Topo IIα promoter. (B) Statistical data showed the acetylation levels of histone H3 in the Topo IIα promoter were shown. (C) Statistical data showed the acetylation levels of histone H4 in the Topo IIα promoter. **P < 0.01, compared to the control group; #P < 0.05, ##P < 0.01, compared to the benzene alone-treated group.