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. 2016 Apr 8;11(4):e0153330. doi: 10.1371/journal.pone.0153330

Fig 4. TSA or MCP30 alters the mRNA levels of regulatory factors in the Topo IIα promoter in benzene poisoning mice.

Fig 4

After all mice were killed, bone marrow mononuclear cells were separated and the mRNA levels of regulatory factors, including SP1 (A), C-MYB (B), SP3 (C), ATF-2 (D), and ICBP90 (E) were determined using RT-PCR. Relative mRNA levels were defined as a ratio of the targeted gene to GAPDH. Representatives of 6 groups with 8 mice each group were shown in left column and statistical data were shown in right column. **P < 0.01, compared to the control group. #P < 0.05, ##P < 0.01, compared to the benzene alone-treated group.