Table III.

Multivariate analysis of covariates for disease-free survival

Parameter	Hazard ratio (95% confidence interval)	P value
At Complete Remission (N=260)
Age	1.017 (1.005, 1.029)	0.006
WBC	1.003 (1.002, 1.005)	<0.0001
Cytogenetics	0.89 (0.61, 1.30)	0.54
MRD at CR	1.47 (1.003, 2.153)	0.048
At 3 Months from Therapy Initiation (N=215)
Age	1.016 (1.004, 1.028)	0.01
WBC	1.003 (1.002, 1.005)	<0.0001
Cytogenetics	0.92 (0.64, 1.34)	0.68
MRD at 3 Months	1.72 (0.79, 3.73)	0.17
At 6 Months from Therapy Initiation (N=166)
Age	1.015 (1.003, 1.027)	0.014
WBC	1.003 (1.001, 1.005)	0.0003
Cytogenetics	0.98 (0.67, 1.42)	0.90
MRD at 6 Months	2.12 (0.70, 6.44)	0.18

WBC, white blood cell count; MRD, minimal residual disease; CR, complete remission