Table IV.

Multivariate analysis of covariates for overall survival

Parameter	Hazard ratio (95% confidence interval)	P value
At Complete Remission (N=260)
Age	1.023 (1.011, 1.036)	0.0002
WBC	1.002 (1.000, 1.004)	0.04
Cytogenetics	0.85 (0.57, 1.25)	0.40
MRD at CR	1.4 (0.94, 2.10)	0.1
At 3 Months from Therapy Initiation (N=216)
Age	1.023 (1.010, 1.036)	0.0004
WBC	1.002 (1.000, 1.004)	0.04
Cytogenetics	0.87 (0.59, 1.28)	0.47
MRD at 3 Months	1.96 (0.85, 4.50)	0.12
At 6 Months from Therapy Initiation (N=166)
Age	1.022 (1.010, 1.035)	0.0005
WBC	1.001 (1.000, 1.003)	0.12
Cytogenetics	0.92 (0.63, 1.35)	0.67
MRD at 6 Months	2.68 (0.89, 8.06)	0.08

WBC, white blood cell count; MRD, minimal residual disease; CR, complete remission