Table V.

Multivariate analysis of covariates for time to disease relapse

Parameter	Hazard ratio (95% confidence interval)	P value
At Complete Remission (N=260)
Age	1.006 (0.992, 1.021)	0.39
WBC	1.005 (1.003, 1.006)	<0.0001
Cytogenetics	0.815 (0.498, 1.333)	0.41
MRD at CR	2.263 (1.432, 3.576)	0.0005
At 3 Months from Therapy Initiation (N=216)
Age	1.003 (0.989, 1.018)	0.67
WBC	1.004 (1.003, 1.006)	<0.0001
Cytogenetics	0.925 (0.570, 1.503)	0.75
MRD at 3 Months	1.976 (0.790, 4.944)	0.145
At 6 Months from Therapy Initiation (N=166)
Age	1.001 (0.987, 1.016)	0.86
WBC	1.004 (1.002, 1.006)	<0.0001
Cytogenetics	1.059 (0.653, 1.715)	0.82
MRD at 6 Months	3.969 (1.214, 12.691)	0.02

WBC, white blood cell count; MRD, minimal residual disease; CR, complete remission