Table 2. Comparison of nPCR, microscopy, and LAMP for the Plasmodium genus detection and species identification*.
| Parasite(s) detected by each method (no. of samples) † | ||
|---|---|---|
| nested PCR | Microscopy | LAMP |
| genus Plasmodium(117) | genus Plasmodium(118) | genus Plasmodium (116) |
| negative (1) | ||
| P. falciparum(77) | P. falciparum(72) | P. falciparum (69) |
| negative (4) | ||
| P. vivax (5)‡ | P. falciparum (4) | |
| negative (15) ¶ negative (18)° | negative(15) | negative(15) negative (18) |
*n PCR=nested polymerase chain reaction; LAMP = Loop-mediated isothermal amplification. † Each row shows results obtained from identical blood samples. Microscopy + LAMP results that were not concordant are shown in bold. ‡ Four of these samples were not detected due to mixed infections. ¶ Samples of patients with fever of unknown origin. Samples provided by the blood bank