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. 2016 Apr 8;58:30. doi: 10.1590/S1678-9946201658030

Table 4. Genotypic and allelic frequencies of the five SNPs in the 141 recruited subjects according to parasitemia determined by the thick blood smear test .

Polymorphisms Detectable Parasitemia N=69 Non-Detectable Parasitemia N=72 Total c 2 p OR [95% CI]
IL6 -147 G/C
Genotypic frequency GG 33 36 69 0.224 NC
GC 33 32 65 0.893
CC 3 4 7
Wild genotype GG 33 36 69 0.066 0.916
Grouped genotype GC+CC 36 36 72 0.796 [0.47-1.77]
Allelic frequency G 99 104 203 0.081 0.976
C 39 40 79 0.928 [0.58-1.64]
IL-12p40 A/C
Genotypic frequency AA 23 31 54 1.689 NC
AC 39 33 72 0.429
CC 7 8 15
Wild genotype AA 23 31 54 1.409 0.661
Grouped genotype AC+CC 46 41 87 0.235 [0.33-1.31]
Allelic frequency A 85 95 180 0.585 0.827
C 53 49 102 0.444 [0.50-1.47]
IL-4 +33 C/T
Genotypic frequency CC 27 32 59 0.556 NC
CT 31 28 59 0.757
TT 11 12 23
Wild genotype CC 27 32 59 0.408 0.803
Grouped genotype CT+TT 42 40 82 0.522 [0.41-1.57]
Allelic frequency C 85 92 177 0.158 0.906
T 53 52 105 0.690 [0.55-1.47]
IL10 -3575 T/A
Genotypic frequency TT 39 47 86 1.372 NC
TA 25 22 47 0.503
AA 5 3
Wild genotype TT 39 47 86 1.135 0.691
Grouped genotype TA+AA 30 25 55 0.286 [0.35-1.36]
Allelic frequency T 103 116 219 1.422 0.710
A 35 28 63 0.233 [0.40-1.24]
TGFβ1 +869 T/C
Genotypic frequency TT 27 33 60 0.826 NC
TC 25 25 50 0.661
CC 17 14 31
Wild genotype TT 27 33 60 0.647 0.759
Grouped genotype CT+CC 42 39 81 0.421 [0.38-1.48]
Allelic frequency T 79 91 170 1.041 0.779
C 59 53 112 0.307 [0.48-1.25]

Note: The c2test was used to determine statistical significance differences between genotypic and allelic frequencies; OR - Odds Ratio, CI - confidence interval; NC - not calculated.