Table 2.
Treatment | Dose (mg/kg) | Onset of myoclonic jerks (min) | Onset of tonic clonic convulsions (min) | % Mortality |
---|---|---|---|---|
Vehicle | 10 ml | 1.05 ± 0.21 | 1.79 ± 0.32 | 100 |
Diazepam | 5 | 60 ± 0 | 60 ± 0 | 0 |
Piperine | 5 | 4.77 ± 0.82 | 12.35 ± 3.04 | 100 |
10 | 18.2 ± 1.35 | 47.6 ± 5.27 | 40 | |
20 | 7.992 ± 0.23 | 21.71 ± 0.95 | 100 |
Significant as compared to saline at ** p < 0.01, *** p < 0.001