Table 1.

Model parameters. The forward and backward transition rates at zero voltage is given in this table with the data of gating charges and fractional electrical distances as used by Millonas et al.²⁶ The instantaneous conductance g_V expressed as ${\displaystyle g_{V\left(t\right)} = g_0+g_{1}V\left(t\right)+g_2{(V\left(t\right))}^2+ g_3{(V\left(t\right))}^3}$, where unit of g_V is μS and g₁ = −8.21 × 10⁻⁴, g₂ = −4.72 ×10⁻⁶, g₃ = 1.49 × 10⁻⁸ with g₀ = 0.0169 is the overall scaling factor representing the cell expression rate. V_r is the reversal potential for the sodium ion channel under study, usually 67.0 mV

Rate index	i (0)(s−1)	i(0) (s−1)	qi	i
1	4779	10.3	2.83	0.053
2	5045	12.1	3.16	0.5
3	1684	2360	0.077	0.78
4	19.8	$\frac{{\alpha }_4 {\beta }_5}{{\alpha }_5}$	5.573	0.12
5	800	59.8	0.16	0.33