Figure 7. Differential sensitivity to TNFα and TRAIL is responsible for the differential requirement of TNFα and TRAIL for IFNα/BV6-induced cell death.
A172 and HT-29 cells were treated for 72 hours with indicated concentrations of TNFα A. or TRAIL B. with (right panel) or without (left panel) 1 μM BV6. Cell viability was determined by MTT assay. Data are shown as percentage of untreated control cells with mean + SD of three independent experiments performed in triplicate; *P < 0.05; **P < 0.01.