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. 2015 Nov 26;7(4):4155–4166. doi: 10.18632/oncotarget.6393

Table 2. Univariate analyses of patient and tumor characteristics for survival.

Event-free survival Overall survival
Variable N used N event HR 95% Lower 95% Upper p-value N event HR 95% Lower 95% Upper p-value
Time from 1st chemo to 3F8 170 75 0.906 0.839 0.978 0.012 46 0.938 0.856 1.029 0.179
Time from ASCT/last chemo to 3F8 170 75 0.726 0.553 0.954 0.022 46 0.889 0.666 1.188 0.426
ASCT (Y vs N) 170 75 0.68 0.413 1.12 0.13 46 0.991 0.546 1.797 0.975
MYCN-amplified (Y vs N) 162 74 0.747 0.473 1.179 0.21 46 0.681 0.380 1.219 0.196
Ultra-High-Risk (Y vs N) 170 75 1.221 0.759 1.966 0.41 46 1.175 0.640 2.157 0.602
HAMA (Y vs N)* 170 75 1.169 0.687 1.989 0.564 46 0.536 0.279 1.022 0.058
High-Dose 3F8 (Y vs N) 170 75 1.507 0.791 2.871 0.212 46 2.220 0.902 5.467 0.083
Pre-MRD (Y vs N) 170 75 1.009 0.617 1.648 0.972 46 1.269 0.696 2.313 0.436
Post-MRD (Y vs N)* 165 72 4.997 2.894 8.627 < 0.001 43 4.304 2.232 8.301 < 0.001
FcGR2a
 HR vs HH 170 75 0.679 0.401 1.149 0.149 46 0.702 0.362 1.362 0.295
 RR vs HH 170 75 0.865 0.469 1.594 0.642 46 0.748 0.336 1.666 0.477
FcGR3a
 VF vs FF 170 75 0.654 0.347 1.234 0.19 46 0.794 0.339 1.86 0.596
 VV vs FF 170 75 0.646 0.332 1.258 0.199 46 0.862 0.357 2.08 0.741
KIR (Y vs N) 170 75 0.864 0.528 1.411 0.558 46 0.953 0.501 1.81 0.882
KIR 2DL1 (Y vs N) 170 75 0.973 0.617 1.534 0.907 46 1.37 0.766 2.45 0.288
KIR 2DL2 2DL3 (Y vs N) 170 75 0.754 0.346 1.643 0.478 46 0.525 0.163 1.693 0.281
KIR 3DL1 (Y vs N) 170 75 0.615 0.371 1.019 0.059 46 0.631 0.332 1.2 0.16
Trial (09–158/159 vs03–077) 170 75 1.370 0.735 2.552 0.321 46 1.883 0.764 4.642 0.169
*

time-dependent variable