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. 2015 Dec 28;7(4):4226–4240. doi: 10.18632/oncotarget.6772

Figure 4. EDIL3 stimulation inhibits anoikis and promotes anchorage-independent tumor growth in PDAC cells.

Figure 4

(A) Detection of purified recombinant human EDIL3 protein by coomassie blue staining. (B) PDAC cells derived EDIL3 promoted tumor angiogenesis in vitro. Scale bar: 200 μm. Treatment with recombinant EDIL3 protein inhibited anoikis as revealed by flow cytometry (C) and caspase-3/7 activity (D), and promoted the colony formation ability (E) of PANC1 and AsPC1 cells in a dose-dependent manner. Scale bar: 5 mm. Ctrl versus 10 nM EDIL3 or 100 nM EDIL3, *P < 0.05, **P < 0.01, ***P < 0.001.