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. 2015 Dec 15;7(4):4724–4734. doi: 10.18632/oncotarget.6619

Figure 2. Giant nuclear bodies (GNBs) are different from nucleoli in cancer cells.

Figure 2

A. 3-D images of nuclei (blue), nucleoli (red bodies) and GNBs (green bodies) in cancer cells. GNBs attach on the surface of nucleoli. B. Magnified image of 3-D images of nuclei (blue), nucleoli (red bodies) and GNBs (green bodies) in cancer cells. Two GNBs attach on the surface of two nucleoli in the nucleus of cancer cells. C. GNBs (green bodies) were removed completely from nucleoli (red nuclear bodies) in nuclei of KG-1 cells after treatment with 0.05% NP40 for 5 min. Cell nuclei (blue) were stained using 4′,6-diamidino-2-phenylindole (DAPI).