Table 1. Correlation between PRDM16 methylation status and clinical parameters of astrocytoma patients.
Variable | PRDM16 | P | |
---|---|---|---|
hypomethylation | methylation | ||
Total (N=50) | 42 | 8 | |
Expression(score) | 0.016 | ||
<8(11) | 6 | 5 | |
≥8(39) | 36 | 3 | |
Sex | 0.377 | ||
Male(34) | 30 | 4 | |
Female(16) | 12 | 4 | |
Age(years)a | 0.307 | ||
<42(23) | 18 | 5 | |
>42(27) | 24 | 3 | |
Grade | 0.047 | ||
low grade (I+II)(20) | 14 | 6 | |
high grade (II+III)(30) | 28 | 2 |
median age is 42 years
Abbreviation: PRDM16, PR domain containing 16