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. Author manuscript; available in PMC: 2017 Apr 7.
Published in final edited form as: Cell. 2016 Mar 3;165(2):449–463. doi: 10.1016/j.cell.2016.02.022

Figure 1. CH235 Lineage, with Time of Appearance and Neutralization by Select Members.

Figure 1

(A) Phylogram of CH235 lineage. Phylogenetic tree is colored by first time (wk post-infection) from which sequences were obtained. Key members of the CH235 lineage are labeled. CH235.6, CH235.7, CH235.8 and CH235.9 VH were complemented with full heavy chain gene regions and paired with the VL from the closest natural antibody. (B) Neutralization dendrograms display single mAb neutralization of a genetically diverse panel of 199 HIV-1 isolates. Coloration is by IC50. See also Figure S1, Tables S1 and S2.