Table 2. Progression free survival rates by clinical parameters.
n | Actuarial 2-year PFS (95 % CI) | Estimated 5-year PFS (95 % CI) | Hazard ratio (95 % CI) | p value (log-rank) | ||
---|---|---|---|---|---|---|
Entire cohort | 28 | 75 % (53–88 %) | 54 % (31–72 %) | |||
MIB labeling index | MIB-1 ≤ 4 % | 13 | 90 % (47–99 %) | 90 % (47–99 %) | 0.18 (0.04–0.44) | 0.0026 |
MIB-1> 4 % | 11 | 48 % (16–74 %) | 12 % (1–41 %) | |||
Percent resection | >80 % | 14 | 83 % (46–95 %) | 48 % (16–75 %) | 0.67 (0.23–2.0) | 0.47 |
≤80 % | 14 | 67 % (34–86 %) | 57 % (25–80 %) | |||
Tumor size | ≤4.1 | 14 | 75 % (41–91 %) | 54 % (21–78 %) | 0.87 (0.27–2.7) | 0.80 |
>4.1 | 13 | 82 % (45–95 %) | 60 % (24–83 %) | |||
Overall resection extent | GTR | 9 | 75 % (31–93 %) | 40 % (7–73 %) | 1.4 (0.41–5.2) | 0.57 |
STR | 19 | 76 % (47–90 %) | 61 % (32–80 %) | |||
Resection extent ± adjuvant radiotherapy | STR + RT | 3 | 100 % (NA) | 67 % (6–95 %) | NA | 0.049 |
STR – RT | 16 | 70 % (38–88 %) | 53 % (23–76 %) |