Postnatal deletion of Mef2c does not impact learning and memory. (A) Short term memory of the conditional Mef2c KO mice was indistinguishable from littermate controls 90 minutes after training (CTL, n=11; KO, n=10). (B) Context-dependent fear conditioning was assessed 24 hrs after training (CTL, n=11; KO, n=10). (C) Cue-dependent fear conditioning was examined 24 hrs after the training (CTL, n=9; KO, n=7). (D) Pain sensitivity was assessed by measuring thresholds of foot shock intensities to flinch, jump, and vocalize. (CTL, n=11; KO, n=10). (E) Mice were assessed in their performance in the novelty recognition test 24 hrs after the training (CTL, N=9; KO, N=7).