Figure 4.
Postnatal deletion of Mef2c does not impact learning and memory. (A) Short term memory of the conditional Mef2c KO mice was indistinguishable from littermate controls 90 minutes after training (CTL, n=11; KO, n=10). (B) Context-dependent fear conditioning was assessed 24 hrs after training (CTL, n=11; KO, n=10). (C) Cue-dependent fear conditioning was examined 24 hrs after the training (CTL, n=9; KO, n=7). (D) Pain sensitivity was assessed by measuring thresholds of foot shock intensities to flinch, jump, and vocalize. (CTL, n=11; KO, n=10). (E) Mice were assessed in their performance in the novelty recognition test 24 hrs after the training (CTL, N=9; KO, N=7).