Table 1.

p Values for multivariate analyses of associations between the listed clinicopathological variables and quantile-normalised expression of each of CEACAM1, CCL2, CCR2 and the STAT3 signature genes^*

	CEACAM1		CCL2		CCR2		STAT3 signature
	T3–T4	T1–T4	T3–T4	T1–T4	T3–T4	T1–T4	T3–T4	T1–T4
Age	0.17	0.039	0.788	0.411	0.686	0.285	0.035	0.017
Gender (male vs. female)	0.58	0.37	0.35	0.38	0.16	0.18	0.80	0.70
Primary tumour site (colon vs rectum)	0.23	0.23	0.67	0.65	0.88	0.87	0.34	0.35
Primary lymphatic presentation	0.092	0.11	0.68	0.51	0.53	0.34	0.42	0.52
Lymphatic invasion	0.86	0.75	0.45	0.70	0.87	0.61	0.54	0.83
Venous invasion	0.36	0.12	0.69	0.90	0.19	0.039	0.80	0.99

^*p Values are indicated for association in a multivariate linear model predicting gene expression as a function of the variables listed in the rows of the table. Separate models are fit for each column of the table; statistically suggestive values (<0.1) are indicated in italics.