Table 1.
Sociodemographic and clinical characteristics of 85 participants in the Detroit Neighborhood Health Study.
| Overall (N=85) |
PTSD status | |||
|---|---|---|---|---|
|
| ||||
| No PTSD (N = 66) |
Lifetime PTSD (N=19) |
Past year PTSD (N= 14) |
||
| Age in years, median (IQR) | 44 (35–54) | 44 (35–54) | 44 (33–58) | 47 (33–58) |
| Gender, N (%) | ||||
| Female | 53 (62.4) | 41 (62.1) | 12 (63.2) | 10 (71.4) |
| Male | 32 (37.7) | 25 (37.9) | 7 (36.8) | 4 (28.6) |
| Race/ethnicity, N (%) | ||||
| Black | 69 (81.2) | 55 (83.3) | 14 (73.7) | 10 (71.4) |
| Non-black | 16 (18.8) | 11 (16.7) | 5 (26.3) | 4 (28.6) |
| Education, N (%) | ||||
| ≤High school | 44 (51.8) | 33 (50.0) | 11 (57.9) | 7 (50.0) |
| >High school | 41 (48.2) | 33 (50.0) | 8 (42.1) | 7 (50.0) |
| Medication usea, N (%) | ||||
| Yes | 35 (42.7) | 28 (43.7) | 7 (38.9) | 5 (38.5) |
| No | 47 (57.3) | 36 (56.3) | 11 (61.1) | 8 (61.5) |
| Cigarette use in lifetime, N (%) | ||||
| Yes | 51 (60.0) | 37 (56.1) | 14 (73.7) | 9 (64.3) |
| No | 34 (40.0) | 29 (43.9) | 5 (26.3) | 5 (35.7) |
| PBMC count (Millions of cells), median (IQR) | 21.00 (17.60–26.80) | 21.52 (17.32–26.25) | 20.75 (17.85–29.35) | 20.90 (18.10–29.35) |
Abbreviations: PTSD, posttraumatic stress disorder; E:N ratio, ratio of end-stage non-proliferative effector cells (E; CCR7-CD45RA+CD27-CD28-orTEMRA) to naïve T-cells (N; CCR7+CD45RA+CD27+CD28+).
a
Medications included antimicrobial agents, cardiovascular-renal drugs, central nervous system medications, metabolic and nutrient agents, hormones and agents affecting hormonal mechanisms, immunologic agents, oncolytics, and drugs used for relief of pain. 3 individuals were missing data on medication use.