Figure 4.
A, change in tumor bioluminescence signal (a), mean FLT PET signal (b), maximum FLT PET signal (c), and volume (d) (mean ± SD) over the course of the experiment in the control, low-dose, and high-dose groups. The values and error bars represent the mean and SD, respectively. Results shown are normalized to their respective baseline value. The P values shown are the results of the ANOVA for each group. For those groups with significant differences, the significantly different pairs are indicated. B, change in mean PET signal (mean ± SD) over the course of the experiment in the control, low-dose, and high-dose groups. Results shown are normalized to the baseline value. The P values shown are the results of the ANOVA for each group. For those groups with significant differences, the significantly different pairs are highlighted. C, change in maximum PET signal (mean ± SD) over the course of the experiment in the control, low-dose, and high-dose groups. Results shown are normalized to the baseline value. The P values shown are the results of the ANOVA for each group. For those groups with significant differences, the significantly different pairs are highlighted. D, change in tumor volumes as measured by MRI over the course of the experiment in the control, low-dose, and high-dose groups. The P values shown are the results of the ANOVA for each group. For those groups with significant differences, the significantly different pairs are highlighted.