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. Author manuscript; available in PMC: 2016 Apr 10.
Published in final edited form as: Autoimmunity. 2015 Apr 10;48(6):389–401. doi: 10.3109/08916934.2015.1030613

Figure 7.

Figure 7

PR deficiency increases the ratio of TFH cells to non-TFH CD4+ T cells in 10 mo.-old female Nba2 mice but decreases this ratio in age-matched male Nba2 mice. Shown are medians (lines) and individual values (symbols) for TFH/non-TFH CD4+ T cell ratios (A), TFH/B cell ratios (B) and TFREG percentage of TFH cells (C). *, p < 0.05; **, p < 0.01 unpaired t test of log-transformed data (A and B) or untransformed data (C). (D – H) Linear regression analysis of serum anti-chromatin Ig AUC levels at 10 mo. vs. TFH/non-TFH CD4+ T cell ratio (D), TFH/B cell ratio (E), TFREG percentage of TFH cells (F), TFH cells/spleen (G), and TREG cells/spleen (H) in all mice. P values for linear regression analyses are shown within each graph.