Table 1.
Clinico-pathological and radiological characteristics of ovarian cancer subtypes
| Carcinoma subtype | HG-serous | LG-serous | Mucinous | Endometrioid | Clear cell |
|---|---|---|---|---|---|
| Percentage (%) | 70–80 | <5 | 3 | 10 | 5–10 |
| Gene mutations | TP53, BRCA1/2 | BRAF; KRAS | KRAS | PTEN;CTNNB-1 | KRAS, PTEN, PIK3CA |
| Precursor | STIC | Serous cystadenoma borderline tumor | Mucinous cystadenoma borderline tumor | Endometriosis | Endometriosis, clear cell adenofibroma |
| Tumor morphology | Cystic and solid; solid; irregular contour | Solid and cystic; papillary projections; Psammoma bodies; | Large, cystic or solid; smooth contour | Smooth contour; solid and cystic; solid nodule in endometrioma | Large, thick wall; cystic with mural nodules protruding into lumen |
| Uni- or bilateral | Bilateral | Bilateral | Unilateral | Unilateral | Rarely bilateral |
| Dissemination | Diffuse abdominal | Abdominal | Ovary | Pelvic | Pelvic |
| Platinum-based-chemotherapy response | High | Intermediate | Low | High | Low |
| Prognosis | Poor | Intermediate | Good | Good | Intermediate |