Figure 2. SPOCK2 mRNA expression patterns.
Developmental SPOCK2 mRNA expression patterns in rat whole-lung tissue (A), lung fibroblasts (C) and AECs (D). Expression was quantified by real-time PCR from fetal life to adulthood, in three to six individual lung samples per stage. The birth level in whole lung tissue and the day-1 level in isolated cells were arbitrarily attributed a value of 100. Values are mean ± SEM. * p<0.05 versus reference level. B. Changes in lung SPOCK2 mRNA expression in newborn rats exposed to hyperoxia from day 5 to day 10. Values are mean ± SEM and results are expressed as a percentage of the control value. * p<0.05.