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. Author manuscript; available in PMC: 2016 Apr 10.
Published in final edited form as: Mol Pharm. 2015 Sep 23;12(10):3650–3657. doi: 10.1021/acs.molpharmaceut.5b00364

Figure 3.

Figure 3

Evaluation of DNA loading efficiency into EVs via electroporation. (A) HEK293T-derived EVs were electroporated in the presence of various initial amounts of 250 bp linear dsDNA (DNA Loaded) and DNA incorporated into EVs was assessed by PicoGreen assay. All data were normalized to background signal generated by electroporated DNA only at each loading amount. (B) Similarly, HEK293T-derived EVs were electroporated in the presence of 5 µg of this DNA, and the number of pulses was varied as indicated. DNA incorporated into EVs was assessed by PicoGreen assay. For both panels, n = 3.