Table 3.

Estimates of 4-year decline in Health ABC physical performance battery^* by AF status at ages 70, 74, 78, and 82.

	AF status	Age 70 Est (95% CI)	P	Age 74 Est (95% CI)	P	Age 78 Est (95% CI)	P	Age 82 Est (95% CI)	P
Model 1	No prior AF	−0.21 (−0.23, −0.18)		−0.29 (−0.30, −0.28)		−0.38 (−0.39, −0.36)		−0.46 (−0.49, −0.43)
	Incident AF	−0.29 (−0.37, −0.21)		−0.38 (−0.46, −0.30)		−0.47 (−0.55, −0.39)		−0.555 (−0.64, −0.47)
	Difference†	−0.08 (−0.16, −0.01)	0.026	−0.09 (−0.164, −0.010)	0.027	−0.09 (−0.17, −0.01)	0.027	−0.10 (−0.18, −0.01)	0.027
Model 2	No prior AF	−0.20 (−0.22, −0.17)		−0.28 (−0.30, −0.27)		−0.37 (−0.39, −0.35)		−0.46 (−0.48, −0.43)
	Incident AF	−0.28 (−0.36, −0.21)		−0.37 (−0.45, −0.30)		−0.46 (−0.54, −0.38)		−0.55 (−0.64, −0.47)
	Difference	−0.08 (−0.16, −0.01)	0.023	−0.09 (−0.16, −0.01)	0.023	−0.09 (−0.17, −0.01)	0.023	−0.10 (−0.18, −0.01)	0.024

Model 1, adjusted baseline age, sex, race, site, and interaction of age-by-female. Model 2, additionally adjusted on baseline BMI, SBP, DBP, smoking, moderate/heavy drinking, abnormal cholesterol, creatinine, and interactions of age with BMI and creatinine, and for hypertension, diabetes, cardiovascular disease, and cancer as time-varying covariates. Est indicates estimate.

^*Health ABC physical performance battery, scored 0-4, employed as a continuous measure.

^†Difference is the difference in 4-year physical function decline between Health ABC participants with and without incident AF at the specified age.