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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Cell Signal. 2016 Feb 19;28(6):552–560. doi: 10.1016/j.cellsig.2016.02.010

Table 1.

Summary of EC50 ± SEM for adenosine- and inosine-stimulated cAMP production and ERK1/2 phosphorylation at the hA2AR and mA2AR.

Agonist/
Inverse Agonist		 EC50 (μM)
hA2AR mA2AR
cAMP
Assay		 ERK1/2
Phosphorylation
Assay		 cAMP
Assay
Adenosine 0.006 ± 0.001 0.211 ± 0.036 0.059 ± 0.02
Inosine 300.7 ± 48.9 89.38 ± 15.12 709 ± 135.2
Adenosine
+
ZM 241385 (100 nM)		 2.45 ± 1.29 1.17 ± 0.10 7.34 ± 4.56
Inosine
+
ZM 241385 (100 nM)		 > 300 > 300 >1000