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. 2015 Dec 11;10(4):625–634. doi: 10.1016/j.molonc.2015.11.011

Figure 3.

Figure 3

AAVrh.8‐sTRAIL combined with lanatoside C slows invasive primary glioma growth. (A) Mice were intracranially injected with primary GBM8‐FM stem‐like glioma neural spheres. After 21 days, mice were divided into four groups which were treated with AAV‐GFP + vehicle, AAV‐GFP + lan C, AAV‐sTRAIL + vehicle or AAV‐sTRAIL + lan C. The arrow indicates the start of treatment. (B) Weekly bioluminescence imaging was used to assess tumor response to treatment. A representative mouse at significant time points is shown. (C) Kaplan–Meier survival curves for the different groups. (D, E) H&E staining of brain slices for the different groups. A representative image is shown.