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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2015 Nov 11;25(4):467–471. doi: 10.1002/pds.3921

Table 1.

Validity of ICD-9 codes for prevalent health conditions.

Condition Validated
events
12-month window for ICD-9 codes 24-month window for ICD-9 codes
PPV
(95% CI)
NPV
(95% CI)
Sensitivity
(95% CI)
Specificity
(95% CI)
PPV
(95% CI)
NPV
(95% CI)
Sensitivity
(95% CI)
Specificity
(95% CI)
Previous MI 40 97% (82–100%) 87% (79–92%) 38% (19–60%) 100% (98–100%) 98% (85–100%) 88% (80–93%) 44% (25–66%) 100% (98–100%)
Angina 26 83% (36–98%) 96% (90–98%) 57% (29–81%) 99% (91–100%) 85% (44–98%) 97% (93–99%) 74% (46–90%) 99% (92–100%)
Coronary heart disease 88 85% (70–93%) 89% (78–95%) 84% (69–92%) 90% (78–96%) 85% (71–93%) 93% (82–97%) 90% (77–96%) 89% (78–95%)
Congestive heart failure 32 72% (47–86%) 99% (91–100%) 90% (57–98%) 95% (88–98%) 69% (46–86%) 98% (91–100%) 90% (57–98%) 94% (88–98%)
Previous stroke 26 81% (45–95%) 93% (85–97%) 52% (26–76%) 98% (92–100%) 77% (45–93%) 93% (85–97%) 52% (27–76%) 98% (93–99%)
Current smoking (ICD-9 codes only) 45 74% (52–88%) 84% (73–91%) 62% (43–78%) 90% (80–96%) 69% (51–83%) 89% (79–95%) 77% (59–89%) 85% (74–92%)
Current smoking (ICD-9 codes + medication use) 45 77% (57–90%) 88% (78–94%) 73% (54–86%) 90% (80–96%) 71% (54–84%) 93% (83–97%) 77% (59–89%) 85% (74–92%)

International Classification of Disease, Ninth Revision (ICD-9) codes from inpatient and outpatient encounters were used to identify prevalent health conditions. Specific ICD-9 codes and validation criteria are listed in Supplemental Table 1. CI = confidence interval, MI = myocardial infarction, NPV = negative predictive value, PPV = positive predictive value.