Table 2.
Univariable and multivariable factors contributing to fatigue.
| Characteristics | Univariable RR (95% CI) |
Multivariable RR (95% CI) |
|---|---|---|
| Age (years) | ||
| Q1 (≤70) | 1.0 referent | 1.0 referent |
| Q2 (>71–76) | 1.1 (0.76–1.5) | 1.2 (0.82–1.6) |
| Q3 (>76–81) | 1.1 (0.76–1.5) | 1.2 (0.89–1.6) |
| Q4 (>81) | 1.4 (1.1–1.9)† | 1.2 (0.95–1.6)¥ |
| Body mass index (kg/m2) | ||
| Q1 Underweight | 1.0 referent | 1.0 referent |
| Q2 Normal | 0.84 (0.71–0.994) | 0.88 (0.57–1.3) |
| Q3 Pre-obese | 0.73 (0.60–0.89) | 0.83 (0.52–1.3) |
| Q4 Obese | 0.71 (0.57–0.88)¥ | 0.81 (0.51–1.3)¥ |
| Geriatric depression scale | ||
| Q1 (≤1) | 1.0 referent | 1.0 referent |
| Q2 (>1–2) | 1.5 (1.1–2.0) | 1.5 (1.1–2.0) |
| Q3 (>2–4) | 1.4 (1.01–1.9) | 1.5 (1.1–2.1) |
| Q4 (>4) | 1.7 (1.3–2.2)§ | 1.6 (1.2–2.0)§ |
| Interleukin-6 (μg/dL) | ||
| Q1 (≤3) | 1.0 Referent | 1.0 Referent |
| Q2 (>3–5) | 1.2 (0.87–1.8) | 1.1 (0.81–1.6) |
| Q3 (>5–7) | 1.3 (0.90–1.8) | 1.2 (0.89–1.6) |
| Q4 (>7) | 1.4 (1.01–1.9)† | 1.1 (0.81–1.5)¥ |
| Mean arterial pressure (mmHg) | ||
| Q1 (≤77) | 1.0 referent | 1.0 referent |
| Q2 (>77–85) | 0.92 (0.73–1.2) | 0.95 (0.72–1.3) |
| Q3 (>85–94) | 0.88 (0.69–1.1) | 0.95 (0.71–1.3) |
| Q4 (>94) | 0.56 (0.36–0.87)‡ | 0.62 (0.40–0.96)† |
| B-natriuretic peptide (pg/mL) | ||
| Q1 (≤74) | 1.0 Referent | –a |
| Q2 (>74–118) | 1.1 (0.79–1.5) | |
| Q3 (>118–251) | 1.0 (0.74–1.4) | |
| Q4 (>251) | 1.0 (0.74–1.4)¥ | |
| β-Blockers | ||
| No | 1.0 referent | –a |
| Yes | 1.1 (0.75–1.5) | |
| Comorbidities score | ||
| Q1 (≤8) | 1.0 referent | –a |
| Q2 (>8–10) | 1.1 (0.83–1.5) | |
| Q3 (>10–13) | 0.95 (0.67–1.4) | |
| Q4 (>13) | 1.2 (0.88–1.6)¥ | |
| Epworth sleepiness scale | ||
| Q1 (≤3) | 1.0 referent | –a |
| Q2 (>3–6) | 0.99 (0.71–1.4) | |
| Q3 (>6–9) | 1.1 (0.76–1.5) | |
| Q4 (>9) | 1.1 (0.85–1.5)¥ | |
| Heart rate (beats/min) | ||
| Q1 (≤57) | 1.0 referent | –a |
| Q2 (>57–64) | 0.90 (0.66–1.2) | |
| Q3 (>64–70) | 1.0 (0.76–1.4) | |
| Q4 (>70) | 0.94 (0.69–1.4)¥ | |
| Hemoglobin (g/dL) | ||
| Q1 (≤12) | 1.0 referent | –a |
| Q2 (>12–13) | 0.97 (0.74–1.3) | |
| Q3 (>13–14) | 0.79 (0.56–1.1) | |
| Q4 (>14) | 0.95 (0.71–1.3)¥ | |
| Married | ||
| No | 1.0 referent | –a |
| Yes | 1.0 (0.83–1.3) | |
| Race | ||
| Black | 1.0 referent | –a |
| White | 1.1 (0.84–1.4) | |
| Sex | ||
| Male | 1.0 referent | –a |
| Female | 0.85 (0.68–1.07) | |
| Social provision scale | ||
| Q1 (≤28) | 1.0 referent | –a |
| Q2 (>28–34) | 0.94 (0.65–1.4) | |
| Q3 (>34–43) | 1.0 (0.75–1.4) | |
| Q4 (>43) | 1.2 (0.91–1.6)¥ | |
Likelihood ratio trend test (¥P > 0.05, †P ≤ 0.05, ‡P ≤ 0.01, and §P ≤ 0.001).
CI, confidence interval; RR, relative risk.
aNot included in multivariable model.