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. 2016 Apr 11;6:24086. doi: 10.1038/srep24086

Table 1. Parameters for Virtual Retina simulations representing midget cells in the foveal region of a primate retina (see ref. 15).

Parameter Value Comment
Outer Plexiform Layer
σC 0.05° Centre gaussian’s sigma
τC 10 ms Centre signal low pass filtering time constant.
τU 100 ms Undershoot high pass filtering time constant.
wU 0.8 Undershoot transient relative weight.
σS 0.15° Surround gaussian’s sigma
τS 4 ms Surround signal low pass filtering time constant.
λOPL 10 Hz/Lum. unit Overall gain of the centre-surround filter.
wOPL 1 Relative weight of centre and surround signal.
Use leaky heat equation True Averaging by gap junctions rather than dendritic spread. Leads to a non-separable spatio-temporal filter, but somewhat more realistic.
Bipolar Cells
λOPL’ 50 Another gain applied right after λOPL, thus without biological meaning, but useful for implementation issues.
gA0 50 Hz Inert leaks in membrane integration.
σA 0.2° Size of the spatial neighbourhood used to estimate local contrast.
τA 5 ms Size of the temporal neighbourhood used to estimate local contrast.
λA 0 Hz Strength of the gain control feedback loop (no contrast gain control in primate midget cells)
Inner Plexiform Layer
τG 20 ms High pass filtering time constant.
wG 0.7 Transient relative weight.
σG No additional pooling for midget cells.
vG0 0 Bipolar linear threshold.
λG 100 Hz Slope in the linear area.
iG0 37 Hz This is below the threshold current (50 Hz). Thus in the dark the threshold is reached only because of the noise (see below), which leads to a irregular Poisson-like spontaneous activity (at ~1 Hz).
Retinal Ganglion Cells (RGC)
gL 50 Hz Leak conductance (thus the membrane time constant is 20 ms)
σv 0.1 Gaussian white noise current’s normalized amplitude. Integration of this current by the RGCs leads to a Gaussian auto-correlated process with time constant 1/gL and variance σv.
ηrefr 3 ms Refractory period
Density 20 cells/° RGC density (for each polarity). That is a mean inter-RGC interval of 0.05°