Figure 3.
Power of PC-Based Selection Statistic
The allele frequency difference at selected SNPs was varied between two populations separated by varying FST. The significance threshold was set to 8.3 × 10−7 based on 60K SNPs tested.
(A) With 50k samples, the power curves for FST = {0.05,0.02,0.01,0.005,0.002,0.001,0.0005} showed a phase change.
(B) Varying the number of samples for FST = 0.001 demonstrated that this phase change was more gradual at smaller sample sizes.
(C) Varying the number of samples at FST = 0.01 showed that the impact of sample size was less pronounced than at FST = 0.001.