Table 2. Effect of B. pilosa on serum chemistry in ob/ob mice.
| Parameter | 0 week | 5 weeks | ||||
|---|---|---|---|---|---|---|
| 0% BP | 0.5% BP | 2.5% BP | 0% BP | 0.5% BP | 2.5% BP | |
| Glucose (mg/dL) | 432.4 ± 15.9 | 456.8 ± 19.9 | 430.9 ± 16.5 | 627.4 ± 19.8 | 563.4 ± 12.1* | 537.3 ± 17.2* |
| Cholesterol (mg/dL) | 149.2 ± 14.5 | 154.1 ± 15.3 | 162.3 ± 14.0 | 233.7 ± 15.7 | 161.0 ± 13.8* | 144.4 ± 12.6* |
| Triglyceride (mg/dL) | 165.3 ± 9.7 | 173.8 ± 8.2 | 171.2 ± 7.6 | 338.5 ± 5.9 | 253.6 ± 1.4* | 231.6 ± 7.1* |
| Uric acid (mg/dL) | 3.6 ± 0.3 | 3.1 ± 0.5 | 3.6 ± 0.1 | 4.7 ± 0.6 | 5.3 ± 0.1 | 5.1 ± 0.4 |
| HDL (mg/dL) | 123.0 ± 2.2 | 120.7 ± 2.4 | 134.3 ± 3.4 | 148.7 ± 2.2 | 92.2 ± 1.0* | 83.2 ± 1.9* |
| VLDL(mg/dL) | 38.1 ± 1.5 | 35.8 ± 1.7 | 36.2 ± 0.5 | 66.7 ± 1.2 | 50.7 ± 0.3* | 44.6 ± 1.7* |
| Insulin (ug/dL) | 0.35 ± 0.01 | 0.33 ± 0.01 | 0.34 ± 0.01 | 1.42 ± 0.04 | 0.95 ± 0.03* | 0.70 ± 0.02* |
Three groups of 5-week-old ob/ob mice were fed standard diet and standard diet containing 0.5% B. pilosa extract (BP) and 2.5% BP for 5 wk. Serum samples from 5 mice per group were collected for biochemical analysis and the data are expressed as mean ± SEM. *P < 0.05 is considered to be statistically significant when compared with control group (0% BP).