Table 3.

Association Results for Advanced Glycation Endproduct Receptor Candidate Variants with Advanced Glycation Endproduct Levels

SNP	Source	Gene/Nearest Gene	MAF	CHR	Position	p-value	β±SE
rs1035798	GWAS	AGER	0.235	6	32,151,222	0.0073	−0.089±0.033
rs7198427	GWAS	MT1A	0.086	16	56,685,080	0.0099	0.130±0.049
rs6499850	GWAS	MT1A	0.095	16	56,687,638	0.014	−0.120±0.048
rs204995	Exome	AGER	0.291	6	32,154,285	0.022	0.076±0.033
rs7197489	GWAS	MT1A	0.181	16	56,683,993	0.031	−0.077±0.036
rs204993	Exome	AGER	0.001	6	32,155,581	0.045	0.064±0.032
rs113092523	Exome	DDOST	0.001	1	20,971,057	0.045	0.850±0.420
rs3130284	Exome	AGER	0.003	6	32,140,487	0.047	0.067±0.035
rs10503574	GWAS	MSR1	0.036	8	15,984,590	0.052	−0.151±0.077
rs1871574	GWAS	MSR1	0.018	8	15,975,574	0.053	0.209±0.108
rs17426435	Exome	PRKCSH	0.061	19	11,546,269	0.054	0.110±0.056
rs3134946	Exome	AGER	0.209	6	32,145,993	0.054	0.067±0.035
rs3134947	Exome	AGER	0.001	6	32,145,205	0.054	0.067±0.035
rs3096697	Exome	AGER	0.197	6	32,134,510	0.054	0.067±0.035
rs204992	Exome	AGER	0.002	6	32,156,908	0.062	0.063±0.034
rs176095	Exome	AGER	0.001	6	32,158,319	0.070	0.061±0.034
rs414836	GWAS	MSR1	0.065	8	16,045,585	0.087	−0.096±0.056
rs204994	Exome	AGER	0.255	6	32,154,998	0.093	0.057±0.034
rs17677443	GWAS	MSR1	0.060	8	16,029,070	0.094	0.099±0.059
rs11786960	GWAS	MSR1	0.461	8	16,010,949	0.096	−0.046±0.027
rs142241539	Exome	AGER	0.001	6	32,130,655	0.10	−0.690±0.420
rs3130349	Exome	AGER	0.184	6	32,147,696	0.12	0.059±0.038
rs448578	GWAS	MSR1	0.066	8	16,042,900	0.13	0.085±0.056
rs6530943	GWAS	MSR1	0.090	8	15,973,590	0.14	−0.074±0.050
rs10103856	GWAS	MSR1	0.065	8	16,048,551	0.16	−0.079±0.056
rs640742	GWAS	DDOST	0.412	1	20,984,554	0.17	0.041±0.029
rs501257	Exome	PRKCSH	0.140	19	11,536,575	0.17	0.055±0.040
rs149461273	Exome	AGER	0.001	6	32,155,917	0.18	0.560±0.420
rs111334879	Exome	DDOST	0.001	1	20,981,976	0.20	−0.360±0.280
rs204989	GWAS	AGER	0.222	6	32,161,852	0.20	0.045±−0.035
rs204990	GWAS	AGER	0.222	6	32,161,430	0.20	0.045±0.035
rs204991	Exome	AGER	0.225	6	32,161,366	0.20	0.044±0.035
rs11125	Exome	LGALS3	0.098	14	55,611,839	0.22	−0.059±0.048

Results listed only for associations with a p-value ≤0.25, MAF: Minor Allele Frequency, CHR: Chromosome, SE: Standard Error.