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. 2016 Apr 11;14:84. doi: 10.1186/s12967-016-0841-9

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© Gigante et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — CD8⁺ T cells isolated from RCC patient TC express elevated levels of miR-29b and miR-198 when compared to normal donor T cells. Real-time PCR analysis of mir-29b (panels a, b) and mir-198 (panels c, d) expression in CD8⁺ T cells from TC RCC and both HLA-matched normal donors, at day 0 (T0; panels a, c) and after 35 day of stimulation (T35; panels b, d). *p < 0.05 for RCC patient TC versus normal donors at T0. **p < 0.005 and *p < 0.03 for RCC patient TC versus normal donors at T35. Data are representative of 3 independent experiments performed. miR16 expression in CD8⁺ T cells from TC RCC and both HLA-matched normal donors at T0 (e) and T35 (f)