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. 2016 Apr 11;16:303. doi: 10.1186/s12889-016-2986-0

Table 3.

Effect estimates of adherence to statin therapy on cardiovascular mortality by calendar period

Calendar years Small model Large model Difference in HR # events
HR 95 % CI HR 95 % CI
1994–2002 0.85 0.55 to 1.34 0.79 0.44 to 1.40 0.06 158
2003–2006 0.58 0.45 to 0.76 0.46 0.35 to 0.59 0.12 642
2007–2012 0.77 0.65 to 0.92 0.54 0.45 to 0.65 0.23 765
Overall (1994–2002) 0.70 0.61 to 0.81 0.53 0.46 to 0.61 0.17 1565
Falsification outcome (1994–2002) 0.93 0.97 to 1.09 0.68 0.58 to 0.80 0.25 1179