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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Am J Psychiatry. 2015 May 18;172(6):543–552. doi: 10.1176/appi.ajp.2014.14030382

Figure 2. Association of PPM1G Methylation and Activation of the Subthalamic Nucleus During a Stop Signal Task in Adolescents (N=393)a.

Figure 2

aAs shown in panel A, PPM1G methylation is positively associated with blood-oxygen-level-dependent (BOLD) activation in the right subthalamic nucleus in 14-year-olds (corrected p=0.038). The graph depicts the percentage of PPM1G methylation and averaged beta values of activation of the right subthalamic nucleus for each individual; a linear fit line was added. In panel B, a coronal section shows methylation differences in activation of the right subthalamic nucleus (t value of activation, with a lighter color indicating a stronger activation) during successful inhibition, indicating an association between PPM1G methylation and activation of the right subthalamic nucleus (coordinates: x=10, y=−15, z=−5).