aAs shown in panel A, PPM1G methylation is positively associated with blood-oxygen-level-dependent (BOLD) activation in the right subthalamic nucleus in 14-year-olds (corrected p=0.038). The graph depicts the percentage of PPM1G methylation and averaged beta values of activation of the right subthalamic nucleus for each individual; a linear fit line was added. In panel B, a coronal section shows methylation differences in activation of the right subthalamic nucleus (t value of activation, with a lighter color indicating a stronger activation) during successful inhibition, indicating an association between PPM1G methylation and activation of the right subthalamic nucleus (coordinates: x=10, y=−15, z=−5).