FIG. 3.

Correlation analysis between the increase in connectivity and change in Symptom Severity Scales (Bonferroni corrected for number of main effect target regions for each reference ROI). (a) Correlation between right DC with substantia nigra connectivity and HAMD Scores (r: −0.386, p = 0.002 [corrected]). (b) Correlation between right DC with substantia nigra connectivity and YMRS scores (r: 0.297, p = 0.02 [corrected]). (c) Correlation between left DCP with right superior temporal gyrus–insula connectivity and HAMD Scores (r: 0.347, p = 0.007 [corrected]). HAMD, Hamilton Depression Rating Scale; ROI, region of interest; YMRS, Young Mania Rating Scale. Color images available online at www.liebertpub.com/brain