Table 2.
Clinical and Demographic Information by Group
| Measures | BPD (N = 30) Mean (SD) | BPM (N = 30) Mean (SD) | HC (N = 30) Mean (SD) | ANOVA |
|---|---|---|---|---|
| Age (years) | 34 (11) | 33 (11) | 31 (10) | NS |
| Age at first episode (years) | 16 (9) | 15 (4) | NS | |
| Hamilton Depression Rating Scale score (17 item) | 20 (3) | 6 (3) | 0 (0) | 0.001 |
| Young Mania Rating score | 2 (2) | 16 (3) | 0 (0) | 0.001 |
| Mean (SD) | Mean (SD) | |||
| Period off medication before scan (months) | 28 (34) | 49 (70) | NS | |
| Number of prior mood episodes (depression) | >20 | >20 | ||
| Number of prior mood episodes ((hypo)mania) | >20 | >20 | ||
| Time since last manic episode (weeks) | 25 (32) | 28 (48) | NS | |
| Time since last depressive episode (weeks) | 35 (30) | 36 (87) | NS | |
| N (%) | N (%) | N (%) | χ2 | |
| Female | 17 (57) | 19 (63) | 18 (60) | NS |
| Caucasian | 25 (83) | 28 (93) | 28 (93) | NS |
| History of psychosis | 11 (37) | 8 (27) | NS | |
| Bipolar I | 12 (40) | 16 (53) | ||
| Bipolar II | 18 (60) | 14 (47) | NS | |
| Past history of alcohol abuse | 15 (50) | 10 (33) | NS | |
| Past history of drug abuse | 13 (43) | 13 (43) | NS | |
| Right-handedness | 19 (83) | 22 (88) | 27 (90) | NS |
HC, healthy control; BPD, depression; BPM, (hypo)mania.