FIG. 7.

Paracrine effects of BM-SMCs on EaRASMC proliferation and matrix synthesis are unaltered by their labeling with SPIONs. Shown are proliferation ratios (A), tropoelastin amounts in spent media (B), total elastic matrix amounts in cell layers (C), and total matrix elastin synthesized on a per cell basis (D). Values shown represent mean ± SD of outcomes measured from n = 6 replicate cultures/condition at 21 days of culture. * indicates significant differences between standalone EaRASMCs versus cocultured EaRASMCs, deemed for p < 0.05.