FIG. 2.
Dynamic changes of cerebral extracellular glucose concentrations from baseline, during and following hypertonic lactate infusion (HL), according to patient subgroups, dichotomized by cerebral microdialysis (CMD) lactate/pyruvate ratio (LPR), or cerebral blood flow (CBF). The graph shows changes (expressed as the % [delta] increase or decrease from baseline) of cerebral extracellular glucose over time following a 3-h intravenous HL, according to patient baseline LPR (A, dichotomized as normal [CMD LPR ≤25; n = 11] vs. elevated [LPR >25; n = 13]) and CBF (B, dichotomized as normal [CBF ≥32.5 mL/100 g/min; n = 14] vs. oligemic [CBF <32.5 mL/100 g/min; n = 8]). Data are expressed as mean ± standard error of mean.