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Stimulation of cells isolated from Dectin-2−/− mice with C. albicans mutants. C. albicans mutants lacking O-, N-, α-, and β-mannan were screened for their capacity to induce cytokines in Dectin-2−/− peritoneal macrophages (A) and splenocytes (B) from naïve mice. Values represent mean ± SEM (n = 8 mice per group, 2 independent experiments). Significance was determined with Mann–Whitney U-test. Statistically different groups are indicated as *P < 0.05; **P < 0.01; ***P < 0.001.
