FIG. 3.

ECM proteins laminin, elastin, collagen I, and fibronectin visualized using immunofluorescent staining (green) with nuclei stained with DAPI (blue) (A). Quantification of ECM components laminin, elastin, glycosaminoglycan (GAG), and fibronectin (B). Levels of these proteins were significantly higher in low oxygen compared to those in normal oxygen at later time points. *p < 0.01. DAPI, 4′,6-diamidino-2-phenylindole; ECM, extracellular matrix. Color images available online at www.liebertpub.com/tec