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. 2016 May;102:214–222. doi: 10.1016/j.ejpb.2016.03.002

Fig. 9.

Fig. 9

Tetracaine transport profile through (a) silicone membrane using an infinite dose of aggregated drug at pH 4, pH 6, pH 7.6, pH 9 and pH 10 and through (b) porcine skin using an infinite dose of aggregated drug at pH 4, pH 7.6 and pH 9. The inset graph represents lag time versus pH. Each point represents mean ± standard deviation (n = 5). ∗p < 0.05 (one-way ANOVA with Tukey’s HSD test).