Figure 1. The HIV glycan shield.
HIV-1 Env glycosylation contains a population of oligomannose-type glycans that can be ascribed to the intrinsic mannose patch (IMP) and trimer-associated mannose patch (TAMP). Monomeric gp120 expressed outside of the context of the trimer only contains the IMP. The Env protein surface (grey) is derived from the crystal structure [25] and the glycans have been modelled in green (Pritchard et al., unpublished). The glycan structure is Man9GlcNAc2.