Table 2.
(A) Pearson correlations for mean fractional anisotropy of overlapping white matter voxels identified for each ROI pair (i.e. Motor ∩ mPFC; mPFC ∩ Ins; Motor ∩ Ins)
% Sig change difference during ACA | ||||
---|---|---|---|---|
Motor − mPFC (r, p) | mPFC − Ins (r, p) | Motor – Ins (r, p) | ||
Mean FA | Motor ∩ mPFC | −0.08, 0.81 | 0.114, 0.74 | −0.002, 0.99 |
mPFC ∩ Ins | 0.53, 0.09 | −0.102, 0.77 | 0.72, 0.012 | |
Motor ∩ Ins | 0.05, 0.88 | −0.03, 0.94 | 0.06, 0.87 | |
% Sig change during ACA | ||||
---|---|---|---|---|
mPFC | Insula | Motor | ||
Mean FA | mPFC ∩ Ins | −0.098, 0.77 | 0.038, 0.91 | 0.675, 0.023 |
CTQ Scores | ||||
Mean FA | mPFC ∩ Ins | −0.198, 0.56 | ||
% signal change difference for the same ROI pair during the anticipation of certain aversion (ACA); (B) the significant mPFC‐Ins pair and the % signal change in each region of the mPFC, insula and motor cortex; (C) the significant mPFC‐Ins pair and CTQ scores.
Significant correlations are highlighted in bold
FA = mean fractional anisotropy; p = p‐values; r = Pearson's correlations.
Abbreviations: ASI, anxiety sensitivity index; CTQ, childhood trauma questionnaire; EPI, echo planar image; mPFC, medial prefrontal cortex; MRS, magnetic resonance spectroscopy; NCEs, negative childhood experiences; rsfMRI, resting state functional MRI