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. 2015 Jun 5;1(3):148–156. doi: 10.1021/acscentsci.5b00160

Figure 1.

Figure 1

(Left) Structure of the GFP chromophore with the phenolic portion highlighted. (Right) Introduced halogen substituents with their corresponding shorthand names, intrinsic denatured pKa values (see Figure S.3), and their differential acidities with respect to Asp148 in the folded protein deduced from the model described below.