Table 3.

Improvement of dry eye symptoms according to compliance with treatment

Dry eye symptoms	Baseline (visit 0)		Visit at 12 weeks
	Complianta	Noncompliantb	Compliant	Noncompliant
Scratchy	1.3 (0.8)	1.2 (0.8)	0.6 (0.7)	0.6 (0.7)
Stinging sensation	1.5 (0.8)	1.3 (0.8)	0.7 (0.7)	0.7 (0.7)
Grittiness	1.6 (0.8)	1.4 (0.8)	0.7 (0.2)	0.8 (0.7)
Painful eyes	0.7 (0.9)	0.6 (0.8)	0.3 (0.5)	0.3 (0.5)
Tired eyes	1.0 (0.9)	1.0 (0.9)	0.4 (0.6)	0.5 (0.6)
Grating sensation	1.2 (0.9)	1.0 (0.8)	0.4 (0.6)	0.5 (0.6)
Blurry vision	0.8 (0.9)	0.7 (0.8)	0.3 (0.6)	0.3 (0.5)
			Difference 12 weeks vs baseline
			Compliant	Noncompliant	P-value
Scratchy			−0.7 (0.7)	−0.6 (0.7)	<0.001
Stinging sensation			−0.8 (0.7)	−0.7 (0.7)	<0.001
Grittiness			−0.9 (0.8)	−0.7 (0.7)	<0.001
Painful eyes			−0.4 (0.7)	−0.3 (0.6)	0.060
Tired eyes			−0.6 (0.8)	−0.5 (0.7)	0.120
Grating sensation			−0.7 (0.8)	−0.5 (0.7)	<0.001
Blurry vision			−0.5 (0.7)	−0.4 (0.6)	0.015

Notes: Data as mean (standard deviation). Compliant (781, 62.2%) and noncompliant (474, 37.8%) are self-reported data.

^aCompliant: always took the three capsules every day.

^bNoncompliant: some/much forgetfulness.